From the editor…
Posted in Editor's introduction on 31st Jan 2013
Sanjeev Rajakulendran and Dimitri Kullmann review the inherited ion channel disorders of the brain, an area that is constantly evolving. As an undergraduate I learnt about the sodium, potassium and calcium ion channels simply to understand the basis of the resting membrane potential; action potentials and muscle contraction with no real reference to clinical neurology. Over time this has changed and highlights that the seemingly academic studies of our preclinical days can help understand the clinical problems of tomorrow. This is a clear and insightful article with a number of highly informative summary tables.
In our article in the series on Norwegian Discoveries in Neuroscience, Krisztina Kunszt Johansen and Jan Olav Aasly explore the genetic basis of Parkinson’s Disease (PD). In this article they highlight how well characterised cohorts of large numbers of ‘sporadic’ PD can reveal new genes especially as we move into the era of next generation sequencing. They also highlight their own contributions to the genetic basis of some familial forms of PD and how the move towards international collaborations is set to revolutionise this whole field of neurogenetics.
Mark Bovey discusses the value of acupuncture for the treatment of migraine. This takes us through the Gallbladder channel and the various different approaches (both practically and theoretically) and the challenge of defining measures of success which can be very difficult in therapies such as this.
Who wrote the first paper on Alzheimer’s Disease in the English language? Andrew Larner tells us in his stimulating account on the life and works of Solomon Carter Fuller, and how his work evolved in its description and importance in the early part of the 20th century with publications in journals such as the American Journal of Insanity!
Pes Cavus is a condition that is not uncommon and is defined as a deformity of ‘a high arched, relatively stiff foot’, as Ball et al discuss in their article in our Rehabilitation Section. There are many causes of this condition and many variants each of which is a consequence in some way of weakness of muscles associated with the foot. This in turn changes the dynamic forces acting on the foot and thus a deformity ensues which brings challenges for the surgeon trying to correct it. This is a very clearly written account that offers much sound advice.
I would like to thank Stephen Kirker for all he has brought to the journal as the Editor of the Rehabilitation Section, as he has now decided to step down from this position. It has been wonderful working with him since the journal came into being in 2001, and he has done an incredible job in ensuring we have always had a first rate article that is interesting and written by the relevant expert. Thank you Stephen. In his place we are delighted to welcome Andrew Bateman.
Mark Manford describes the treat that lies in store for 2013 in a new series on Epilepsy. As Mark states, he wrote one of our very first series of articles a decade ago. Indeed ACNR has now been going for 12 years. As the founder (with Rach Hansford) and Co-Editor in chief I am especially grateful for all the support and help I have had in taking this journal from an idea to a regular, much read publication. However, all good things must come to an end, and so I have decided that it is now time to hand it over to my colleague Mike Zandi.
I will continue in an advisory capacity, but I think it is time for new ideas and leadership.
Happy New Year!
Roger Barker, Co-EditorDownload this Article