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From the Editor…

Posted in Editor's introduction on 27th Feb 2018

Published online: 26/2/18

Welcome to the latest issue of ACNR


Considerable attention is being directed towards identifying neurodegenerative diseases of the brain during their so-called ‘prodromal’ phase to facilitate early diagnosis and enrolment of patients in clinical trials. Kerala Adams-Carr and Alastair Noyce from London highlight current challenges regarding screening populations at risk of Parkinson’s disease. They endorse a two-step approach incorporating the identification of at-risk individuals in the older population, and then using more targeted screening tests to further refine those most at risk.

Vikram Thakur and Steven Smithies from Cambridge propose a schematic model to explain how disrupted functional connectivity between the prefrontal cortex and angular gyrus might be the neurobiological substrate for alterations in the sense of agency seen in patients with schizophrenia.

Regular contributor JMS Pearce from Hull writes this issue’s interesting history of neurology article about Frederick Batten, a former doyen of Edwardian era Queen Square who made major contributions to the literature on subacute combined degeneration of the cord, myotonic dystrophy, and who described the fatal paediatric onset disease, neuronal ceroid lipofuscinosis, now known as Batten’s disease.

Also in this issue, Charles Wade from London writes a synthesis of four recently published large case series in the rapidly evolving field of MOG antibody-induced demyelination.

Stacey Fawcett writes a moving, personal perspective on watching her grandmother engulfed by Parkinson’s disease.

ACNR’s conference editor Angelika Zarkali, together with Sam Shribman, and ABN honorary secretary, Jon Sussman all preview the 2018 ABN meeting in Birmingham. ACNR’s consulting and founding editor, Roger Barker previews the Fifth World Parkinson Congress in Kyoto, and there are previews of Pain Therapeutics in London, and Neurology 2018: Leading Edge Neurology for the Practising Clinician in London.

Conference reports are from Tom Balchin, Claire Williams, Peter Sandercock, Georgios Korres, and Mehran Manoosi. Book reviews are from Melanie Hart and Ranjith Manon.

We hope you enjoy this edition of ACNR.

Todd Hardy, Co-Editor