Category: Case Reports

Eslicarbazepine use in Multiple Sclerosis with refractory trigeminal neuralgia

Posted on 15 March, 2013 - Case Reports

First published online at BJMP 2013;6(1):a602 When associated with Multiple Sclerosis (MS), Trigeminal Neuralgia (TN) is often bilateral and more refractory to treatment. carbamazepine is the first line of treatment for TN, however, common side effects of carbamazepine such as hyponatremia occasionally limit its use. We report the case of a 62 year old female patient…

A paediatric technique for regaining adult bowel control

Posted on 15 March, 2013 - Case Reports

Faecal incontinence affects 1-10 % of adults and in 0.5-1% is severe enough to impair daily quality of life1. The condition remains a socially stigmatising problem with considerable emotional, psychological and physical consequences. Dietary modification, laxatives, constipating agents, suppositories, enemas, bowel retraining and biofeedback are amongst the conventional methods used to address the problem, aiming…

Epilepsy Aggravated by Sodium Valproate in MELAS caused by the A3243G Mitochondrial DNA Mutation

Posted on 15 March, 2013 - Case Reports

A female patient was diagnosed with sensorineural deafness aged 37. She then presented at the age of 45 years with a progressive cerebellar syndrome. Blood DNA analysis detected a nucleotide 3243 A–>G mutation in the mitochondrial DNA confirming a diagnosis of Mitochondrial Encephalomyopathy with Lactic Acidosis and Stroke-like episodes (MELAS). At the age of 48…