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  • Mechanism of Functional Neurological Symptoms

  • Posted in Clinical Review Article

  • 19th Jun 2013

  • What’s in a name? Words used to describe patients with functional neurological symptoms suggest either that we know clearly what the mechanism is (psychogenic,psychosomatic, conversion disorder), or that we have no idea (medically unexplained). Added to this is a pervasive colloquial use of terms in doctor-to-doctor communication about patients with functional neurological symptoms which betrays […]

  • Hippocampal Plasticity – An Update

  • Posted in Clinical Review Article

  • 19th Jun 2013

  • It is forty years since the first full report of long-term potentiation (LTP), a presumed cellular substrate for learning and memory. This review will provide an update on some recent advances in our understanding of the mechanisms underlying hippocampal LTP and address their potential clinical relevance. Introduction The hippocampus plays a fundamental role in learning […]

  • New Developments in Susac’s Syndrome

  • Posted in Clinical Review Article

  • 13th Mar 2013

  • The diagnosis of Susac’s syndrome has been facilitated greatly by appreciation of distinctive magnetic resonance imaging (MRI) findings. As a result there is now increased recognition of what was once thought to be a very rare disease. The aim of this review is to provide an update on the latest developments in Susac’s syndrome and […]

  • Inherited Ion Channel Disorders of the Brain

  • Posted in Clinical Review Article

  • 31st Jan 2013

  • The last two decades have witnessed a rapid increase in the number of inherited disorders caused by ion channel mutations. One of the major challenges is to delineate the full clinical spectrum of these ‘channelopathies’. Among this expanding group, neurological ion channel disorders are among the best characterised, reflecting the fundamental importance of electrical excitability […]

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  • Acupuncture for Headache

  • Posted in Clinical Review Article

  • 31st Jan 2013

  • Acupuncture has a long history as part of Chinese medicine. In Western countries it is now one of the major complementary therapies, with lifetime use in adult populations as high as 34%.1 Headache is one of the more common presenting conditions in acupuncture general practice2 and use of the therapy by headache sufferers in tertiary […]