First published online at BJMP 2013;6(1):a602 When associated with Multiple Sclerosis (MS), Trigeminal Neuralgia (TN) is often bilateral and more refractory to treatment. carbamazepine is the first line of treatment for TN, however, common side effects of carbamazepine such as hyponatremia occasionally limit its use. We report the case of a 62 year old female patient…
Category: side effect
Epilepsy Aggravated by Sodium Valproate in MELAS caused by the A3243G Mitochondrial DNA Mutation
A female patient was diagnosed with sensorineural deafness aged 37. She then presented at the age of 45 years with a progressive cerebellar syndrome. Blood DNA analysis detected a nucleotide 3243 A–>G mutation in the mitochondrial DNA confirming a diagnosis of Mitochondrial Encephalomyopathy with Lactic Acidosis and Stroke-like episodes (MELAS). At the age of 48…
