120 participants across four continents gathered in London in November 2024 to mark the 20th anniversary of the discovery of PINK1 mutations linked to Parkinson’s disease.
The meeting combined past discoveries in the field including historical videos of the original Sicilian PINK1 families affected with Parkinson’s to translational talks notably an update of Phase I clinical data from the USP30 deubiquitinase inhibitor trial initiated in Parkinson’s patients in 2024.
Plenary talks were given by Nicholas Wood (UCL, UK) who discovered PINK1 mutations and Richard Youle (NIH, USA) who discovered the role of PINK1 and Parkin in mitophagy and received the Breakthrough Prize in Life Sciences in 2021.
The event was sponsored by the Biochemical Society, Aligning Science Across Parkinson’s (ASAP), Cure Parkinson’s Trust and Parkinson’s UK.
PINK1 meeting organisers: From L-R: Miratul Muqit, Nicholas Wood, Helene Plun-Favreau.
