…that the “intellect may be unaffected throughout”, as per James Parkinson’s original 1817 description of the disease, but noted that “in the later stages of the disease … mental weakness…
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…brain architecture? Osler noted that: “It is much more important to know what sort of a patient has a disease than what sort of disease a patient has.”Case-control studies of…
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…disease pathogenesis. However, in support of a real pathogenic role is the finding that gut microbiota or gut-derived molecules obtained from pwMS can modulate disease in the main MS animal…
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…Parkinson’s disease. Mov Disord. 2012;27:1262-7. Shine JM, et al. The role of dysfunctional attentional control networks in visual misperceptions in Parkinson’s disease. Hum Brain Mapp. 2013; EPub Ahead of Print….
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Summary MND exhibit variable phenotypes ALS is the commonest and most lethal of the phenotypes Cognitive impairment is a feature of MND Introduction Motor neuron disease (MND) encompasses a group…
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…typically improve motor problems in Parkinson´s disease (PD). Over the disease course, however, the response to levodopa doses becomes shorter and patients become aware of the recurrence of their parkinsonian…
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…an unarguable success. Personalised Medicine The most recurring theme throughout the week (plenary lectures by Susan Fox then Rejko Kruger) was the subject of Personalised Medicine in Parkinson’s disease (PD)….
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…governments on Alzheimer’s disease”, organised by the Global Coalition on Aging (GCOA) and the other on “The Importance of Sharing Global Alzheimer’s Disease Data in Search of Novel Treatments and…
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…years since its proposal. Current molecular classification of frontotemporal dementias categorises Pick’s disease as 3R FTLD-tau, sometimes with coexistent TDP-43 pathology [21]. Accordingly, the term “Pick’s disease” may now be…
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