23 September 2024: Amneal Pharmaceuticals has announced that it has launched CREXONT® (carbidopa and levodopa) extended-release capsules for the treatment of Parkinson’s disease. CREXONT® is a novel, oral formulation of carbidopa/levodopa (CD/LD) that combines both immediate-release granules and extended-release pellets. “We are pleased to launch CREXONT and make it broadly available to healthcare providers and patients. The…
Category: parkinson’s disease
Phase 1 study of UB-312 shows promise in Parkinson’s disease
In a study published in Nature Medicine on 18th September 2024, Parkinson’s patients reported improved daily movement with Vaxxinity’s Parkinson’s drug UB-312. The small trial, which included work from researchers at the University of Texas, the Mayo Clinic, and the Michael J. Fox Foundation for Parkinson’s Research, included only 20 people with Parkinson’s. However, it…
Gait freezing: soft robotic, wearable device improves walking for individual with Parkinson’s disease
Robotic exosuit eliminated gait freezing 5 January, 2024; Gait freezing is one of the most common and debilitating symptoms of Parkinson’s disease, with people suddenly losing the ability to move their feet, often mid-stride, resulting in a series of staccato stutter steps that get shorter until they stop altogether. These episodes are one of the…
Phase 2 Trial of NLY01 in Parkinson’s Disease: Topline results
– This randomised, double-blind, placebo-controlled trial was designed to assess the safety, tolerability, and efficacy of NLY01 in subjects with early, untreated PD. – The primary endpoint, change from baseline in the sum of MDS-UPDRS Parts II and III after 36 weeks of NLY01 treatment, compared with placebo, did not reach statistical significance. – Age was identified as a significant…
New real-world data for ONGENTYS®▼ (opicapone) released at the MDS
New data presented 12-16 September at the MDS 2020 Virtual Congress further support the efficacy and tolerability of ONGENTYS® (opicapone) observed in pivotal Phase III studies. Opicapone is a once-daily catechol-O-methyltransferase (COMT) inhibitor, approved for the treatment of end-of-dose motor fluctuations in adult PD patients taking levodopa. Data from OPTIPARK study demonstrated consistently low incidence of treatment-related adverse events in clinical practice from the…
Topline results of Phase 1-2 CDNF trial
Industry news from Herantis Pharma
MasterClass on the non-oral therapies and new NICE guideline for Parkinson’s
With publication of the new NICE guideline for Parkinson’s, Parkinson’s Academy is holding a series of roadshows exploring the non-oral therapy pathway in detail
In Parkinson’s disease, patients may suffer from delayed ON as well as wearing OFF – which is more important?
Report from Britannia Pharmaceuticals on their plenary session on PD treatment, held at the 9th CONy Congress in Budapest, Hungary, March 2015
